Perimenopause: How to Start An Upward Spiral | M+E Mood Me

Feel like you're losing yourself? Award winning Mood Me is a daily multi nutrient for your mind and brain from M+E and is your first step to get you back.

MOOD ME: Winner, Foundational Nutrition, Nourish Supplement Awards 2026

SHOP MOOD ME

"I've been taking Mood Me for a month now, and from the first day I could feel my mood lift.... I've tried many supplements before which haven't had any noticeable effect but these are totally different - I can completely notice the difference, my mood has lifted significantly and I feel calmer, more positive and more in control.""

Verified buyer ★★★★★

 

Hope starts here

For a lot of women, perimenopause creeps up quietly. Somewhere in your late 30s to 40s, maybe earlier, things start to feel different. You're more tired than you used to be. Your head feels foggy. Memory feels scatty. Your moods don't feel as steady as they did, and you can't always put your finger on why.

And it isn't just physical. Not feeling like yourself can be frightening, especially when you don't understand why it's happening. You might worry that something is seriously wrong, or that this is just how life is going to be now.

Some women describe a real sense of grief, for the person they used to be: the one with energy, patience and a sharp mind, who knew how to handle things.

Wanting to get back to feeling like yourself is completely understandable, and many people feel sad, scared or angry about losing their sense of self.

If that sounds familiar, you're not imagining it, and you're definitely not on your own. It's one of the most common things women talk to us about.

A note from me

I started M+E when I was 50, after going through my own perimenopause, so I know first hand how unsettling it can be. After more than 20 years working in psychology, counselling and coaching, with plenty of my own ups and downs, I knew how much the brain depends on good nutrition. But I couldn't find a supplement that ticked all my boxes.

I'm not good at taking pills, so I wanted something I'd actually manage to take every day: as many ingredients as possible in as few capsules as possible, and easy to swallow.

I also know just how hard it is to find the willpower to eat well when you're feeling flat and exhausted. I wanted a simple first step, something that would help me start making the healthy choices I knew I should be making.

So I spent two years creating it: clean, vegan, made in small batches here in the UK by people I know and visit, with everything that I needed to be in it and nothing else.

I know that perimenopause can make you feel like you're losing the person you used to be. It's how I felt. I wanted a simple, easy action that would help me start my upward spiral.

If Mood Me can be the one small, simple step that you can take to help you look after yourself when energy is low, it's doing exactly what I made it for.

Getting the right nutrition every day is one practical thing you can do for yourself while your body goes through a lot of change.

No supplement can completely stop perimenopause or treat all its symptoms, and we'd never tell you otherwise.

But you can give your brain the powerful, quality ingredients it needs.

"Having taken Mood Me for almost a month I've found it has helped relieve tiredness… leaving me with a sense of wellbeing. I will be ordering more."

Verified buyer ★★★★★

Why it starts with your brain

We tend to think of perimenopause as something happening to our bodies, but actually so much of it is really happening in your brain.

Your brain is the control centre for how your body works and how you feel, including your hormones and energy levels. A small area called the hypothalamus works with the pituitary gland to send the signals that keep your hormones, body temperature, sleep, energy and appetite in balance.

Oestrogen acts on many parts of the brain too, including the areas involved in mood, memory and energy.

So when your hormone levels start to rise and fall unpredictably, your brain feels it, and that's often why perimenopause can show up as tiredness, brain fog or feeling not quite like yourself.

Your brain is also hungry: it makes up around 2% of your body weight but uses about 20% of your energy every day.

That's why we believe looking after your brain is the foundation for getting back to feeling like yourself.

Your brain's messengers

Your brain relies on chemical messengers called neurotransmitters, such as serotonin and dopamine.

They're involved in how you feel, how motivated you are, how well you focus and how you respond to stress.

Your body makes them from amino acids in your food, like tryptophan and tyrosine, and needs other nutrients along the way. Pantothenic acid, for example, contributes to the normal synthesis of some neurotransmitters, and vitamin B6 contributes to normal psychological function.

 

When your hormones are shifting, it can feel like everything is running on empty.

The tiredness that hits mid afternoon.

The foggy head when you're trying to think.

The shorter fuse.

The feeling that there's nothing left at the end of the day for the people you love.

We know how much that takes out of you.

 

What we want for every woman going through this is simple:

to feel more like herself again, with the energy and headspace for her life, her work and her relationships.

Your gut and your brain

Your gut and your brain are in constant conversation, through nerves, hormones and the immune system.

Scientists call this the gut brain axis, and it's one of the most exciting areas of research right now.

Your gut is home to trillions of microbes, known as your microbiome, and emerging research is exploring the role they may play in mood and brain health. Most of your body's serotonin is actually made in your gut, not your brain.

How to start an upward spiral

Good sleep, moving your body, eating well, staying connected to the people around you and getting the right support all feed into how you feel, and the right nutrition is part of that foundation too.

But when you're not feeling like yourself, knowing what's good for you isn't the same as having the energy, capacity and bandwidth to do it, and every one of those things can feel like a huge step.

That's where a supplement can come in. It's one simple thing you can do for yourself, even on the hard days, to help start the upward spiral.

Where Mood Me fits

Mood Me is our multi nutrient for mind and brain. It brings 31 nutrients together in two capsules a day, so you don't have to juggle a cupboard full of separate pots.

Perimenopause often brings tiredness, brain fog, mood changes and broken sleep. Nutrients play a well established role in the things that matter most at this stage of life.

Here's where the nutrients in Mood Me fit:

Energy

• Vitamins B6 and B12 contribute to normal energy yielding metabolism
• Vitamin B6, vitamin B12 and folate contribute to the reduction of tiredness and fatigue

Focus and clear thinking

• Pantothenic acid contributes to normal mental performance
• Zinc contributes to normal cognitive function

Mood and emotional wellbeing

• Vitamin B6, vitamin B12 and folate contribute to normal psychological function

Hormones

• Vitamin B6 contributes to the regulation of hormonal activity
• Pantothenic acid contributes to the normal synthesis and metabolism of steroid hormones and some neurotransmitters

Bones

Oestrogen helps look after your bones, so bone health becomes more important as levels fall.

• Vitamin D contributes to the maintenance of normal bones
• Vitamin K contributes to the maintenance of normal bones

What it means for your everyday

When it feels like so much is changing that you can't control, looking after your nutrition is one small, practical thing you can control. You can do something powerful for yourself.

Mood Me is designed to make that feel easy rather than like another job on the list.

• One simple daily habit. No more researching, comparing and juggling separate pots. Two capsules and you're done.
• Feeling looked after. A moment in your day that's just for you, at a time of life when you're often busy looking after everyone else.
• Peace of mind. You know exactly what's in every capsule, where it's made, and that there's nothing in there you don't need.
• Taking back a bit of control. Nutrients that play a role in energy, psychological function and hormonal activity, at a time when those things can feel like they're running the show.
• It fits your life. Swallow the capsules or split and sprinkle them onto food, and skip or pause your subscription whenever you need to.

It's the everyday nutrition many women tell us they want to get right as their body changes. Everything made easy. Everything all in one place.

"Still getting used to this tablet but I feel it is gradually working for me! I do feel more energised at times, better mood, and better outlook on things. I was lacking motivation and I seem to have got this back after a couple of weeks of taking this! My friend also started the tablet at the same time, and has had good benefits. I like that all the other supplements I need are in one tablet!"

Verified buyer ★★★★★

Made with care

We make Mood Me in small, fresh batches at a family run manufacturer in Sussex in the UK, so every pack is made recently to the highest standards.

We know how much trust it takes to choose a supplement when you're not feeling yourself, so we take that seriously. The full ingredients list is in big print on every pouch making it easy to see everything that is the capsules.

And there's nothing in there that doesn't need to be.

No bulking agents, no fillers and no unnecessary additives, so every capsule is filled with 100% active ingredients.

That's possible because we use Trufil encapsulation, a filling process that means no bulking agents are needed, so we can fit more active ingredients into every capsule. Mood Me is also completely vegan, capsule included.

We've also chosen bioavailable forms of our ingredients wherever we can, such as methylated B vitamins, which are already in the active form your body uses, so they're ready to go to work.

Mood Me is also award winning. It won Foundational Nutrition at the Nourish Supplement Awards 2026, and sits alongside the multiple gold awards across the M+E range.

"I like that all the other supplements I need are in one tablet."

Verified buyer ⭐️⭐️⭐️⭐️⭐️

Why Mood Me

There are a lot of supplements out there, and it's hard to know what's worth your money. Here's what makes Mood Me different.

More than a multivitamin

Most multivitamins stop at vitamins and minerals.

Mood Me goes further.

Alongside methylated B vitamins and essential minerals, it contains a psychologist designed blend of amino acids (L-tryptophan, L-tyrosine, L-glutamine, acetyl L-carnitine, glycine and DL-phenylalanine) together with probiotics.

It's a unique combination, created by us, that you won't find in any other supplement.

• One formula, not a cupboard full of pots. 31 nutrients for mind and brain in two capsules a day.
• Nutrients that matter at this stage of life. Vitamin B6 contributes to the regulation of hormonal activity, and B vitamins contribute to the reduction of tiredness and fatigue.
• Gut and brain, together. As well as nutrients for mind and brain, Mood Me contains specific live cultures for neurotransmitters, because we believe looking after your brain means looking after your whole body.
• Your daily vitamin D, taken care of. No extra supplement needed.
• Award winning. Winner of Foundational Nutrition at the Nourish Supplement Awards 2026.
• Made in small, fresh batches by a family run manufacturer in Sussex.
• Nothing you don't need. Trufil encapsulation means no bulking agents or fillers, just 100% active ingredients.
• Completely vegan.
• Easy to take your way. Swallow the capsules, or split them and sprinkle onto food.
• No commitment. Subscribe and save, and skip, pause or change your order whenever you like, or simply buy a one off pack.

 

"I also love the fact that they are packed with so many vitamins."

Verified buyer ★★★★★

What's inside and how to take it

What's inside

• Methylated B vitamins (B2 Riboflavin-5'-phosphate
  B6 Pyridoxal-5'-phosphate (P-5-P) 
  B9 L-methylfolate or 5-MTHF
  B12 Methylcobalamin)
• Vitamin D3 + K2
• Essential minerals (Copper, Manganese, Selenium, Zinc)
• Targeted amino acids (L-Tryptophan, L-Tyrosine, L-Glutamine, Aceyt-l-Carnitine, L-Glycine, DL-Phenylalanine)
• Probiotics

How to take it

Two capsules a day with food. Each pack lasts 30 days. Can be Split + Sprinkled.

Subscribe and save

Subscribe and save 10% on every delivery. You can skip, pause or change your order whenever you like, so it fits around you. Prefer not to subscribe? You can buy a one off pack instead.

"I am truly grateful for their supplements and their support when I needed it. Thank you for bringing these wonderful supplements into the world!"

Verified buyer ★★★★★

Verified Reviews and FAQs

What customers say

"I have noticed a steady improvement in my mood already which is a huge relief!"

"I also love the fact that they are packed with so many vitamins. I am truly grateful for their supplements and their support when I needed it."

 

Questions

Is Mood Me a treatment for perimenopause? No. It's a food supplement, not a medicine. It doesn't treat, prevent or cure perimenopause or any of its symptoms. Please speak to your GP about symptoms and treatment options.

Can I take it alongside HRT or other medication? Please check with your GP or pharmacist before taking Mood Me if you take any medication, including HRT, the contraceptive pill or antidepressants.

How is Mood Me different from Happy Me? Mood Me is our all round daily multi nutrient. Happy Me is a separate formula with different ingredients, including 5-HTP.

How long until I notice anything? Everyone is different, and we can't promise any particular result. Most people take Mood Me as part of their daily routine for at least a couple of months.

 

Looking after yourself

Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Not suitable for under 18s. If you take any medication, including HRT or antidepressants, or you're pregnant or breastfeeding, please speak to your GP or pharmacist first.

Talk to your GP first

If you think you might be in perimenopause, your GP is the best place to start.

Mood Me isn't a replacement for medical support. It's a food supplement, designed to sit alongside a balanced diet and whatever support is right for you.

If you're struggling with your mood, please talk to your GP. If you feel you can't cope or you're in crisis, you can call Samaritans any time, day or night, on 116 123, or call NHS 111. In an emergency, call 999.

You can find more support from Mind at mind.org.uk and information on perimenopause and menopause on the NHS website.