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What is the Best Supplement for Depression: Happy Me Ingredients

I think we all accept that nutrients can help keep us well. We need them for our bodies to function properly. Lack of vitamins has been linked over hundreds of years to various illnesses.

In 2020 Vitamin D3 has been backed by science to help support our immune systems [16].

So it follows that nutrients also have an impact on your brain and your mental health.

Happy Me is a pioneering and unique superblend of nutrients to support your mental health especially if you are struggling with depression, low mood, feeling flat and poor sleep.

It is designed to naturally boost your serotonin and dopamine levels and ease your symptoms of depression if you would rather not take an antidepressant.

Would like something to naturally boost your serotonin and dopamine levels?

When your body and brain start running low on certain indispensable nutrients ā€“ energy, neurotransmitters, and essential hormones levels start to fall and a simple nutrient infusion can truly turn your life around.

There are certain things that can be clues that your reserves are running low:
depression, chronic fatigue, anxiety, poor physical and mental stamina, irritability, cognitive decline, learning difficulties, memory problems, and sensitivity to stress.

I thought it would be helpful if I wrote a little bit about each ingredient in the M+E superblends and how it can help you.

Iā€™ve kept it focussed on mental and brain health benefits but all the ingredients have a cascade of wonderful effects on both your mind and body.


Happy Me is a serotonin and dopamine supplement.

Are you looking to naturally enhance your mood?

Are you struggling with low mood, depression and low energy levels would like something natural to help?

Are you feeling flat and numb and would like something to bring back the joy in your life?
Happy Me is a combination of ingredients that have been put together by a psychologist specifically to support your brain health to help you feel happier, balanced and recharged [1].


Better mental health starts with the right ingredients which is why the first one in all our M+E unique superblends is
our trademarked, psychologist designed ingredient that you will only find in 360ME. And nowhere else.

MoodNutritionPlusĀ® is a combination of 4 nootropics:

Improves mental and physical energy, improves brain power, lowers inflammation, boosts circulation, increases mental focus and increases fat burning [28].

Turns into dopamine which helps you feel joyful, energised and motivated [31]. Dopamine also influences serotonin, and together, they play a central role in regulating your mood [19].

Helps produce serotonin, which has several health benefits including helping to promote better sleep, providing relief from anxiety and depression, providing increased emotional well-being. It alleviates the symptoms of low serotonin which include negativity, depression, seasonal affective disorder, worry, anxiety, obsessive thoughts, and irritability [17].

L -Glutamine
Is a vital nutrient for the brain helping you to feel calm and relaxed as it reduces anxiety, depression and improves sleep.
Glutamine has important roles in immunity, surgery and burn recovery and also helps your intestines to rebuild and repair improving gut health and digestion [27]

In Happy Me we have put together MoodNutritionPlusĀ® together with:

DL- Phenylalanine
Helps produce dopamine, reduces brain fog, balances hormones, lifts depression, overall enhances mood, reduces pain and promotes greater feelings of happiness and fulfilment [30].

Has antidepressant effects due to increasing brain levels of serotonin, dopamine, and norepinephrine [37]. It needs vitamin B12Ā and folate to make serotonin. Many people who are depressed are deficient in B vitamins, so itā€™s important takeĀ vitamin B12 and folate (especially in the form of L-5 MTHF) at the same time.

It is effective usually within one week of starting to take the supplements, it doesnā€™t interact with prescription medications and has few side effects compared to antidepressants.

5 HTP originates from from the seeds of an African plant known as Griffonia simplicifolia. Itā€™s part of the tryptophan pathway and is used in the regulation of mood, appetite, gut function and sleep. It plays an important role in reducing anxiety, stress and depression [35].

Vitamin B Complex
All B vitamins in our M+E superblends are methylated.

What is methylation?
Methylated vitamins are the active versions of vitamins which your body can readily make use of, while un-methylated vitamins must go through a conversion process before your body can actually use them.

The problem is that many people are unable to make that conversion in their bodies because they have a genetic mutation that prevents it.

All humans have a gene called the MTHFR gene which is responsible for converting some vitamins into their usable state by the body.

60% of the U.S. and 40% of Australian and British people population have a mutation to this gene.

For all individuals who have the gene abnormality, the absorption of B-complex vitamins is either largely inefficient or lacking altogether.

So those vitamins remain mostly unabsorbed, and can simply build up to the point of toxicity.

Taking methylated B vitamins means that you can absorb them in a body ready form.

Sometimes this is the key that unlocks the optimal functioning of our brains and bodies.

Vitamin B1 (Thiamine HCL)
Thiamine is very important to our brain for energy, positive mood, its powerful anti-stress properties as well as being useful for focus and concentration. Low energy, depression, fatigue, PMS and sleep disorders may be signs of mild deficiency (low levels of B1) which can be corrected with supplements [12]

Vitamin B2 (Riboflavin 5ā€™-Phosphate)
Riboflavin helps our brain with energy, mental clarity and a healthy mood through being an important factor in the production of serotonin as part of the tryptophan and Vitamin B3 pathway [13]

Vitamin B3 (Niacin Nicotinamide)
Niacin helps our brain with energy, mental clarity and a healthy mood through being an important factor in the production of serotonin as part of the tryptophan and Vitamin B2 pathway [36].
It also supports our digestive system and increases protection of our skin to sun damage.

Vitamin B5 (Calcium Pantothenate)
Vitamin B5, also called pantothenic acid, is one of the most important vitamins for human life. Itā€™s necessary for making blood cells, it helps you convert the food you eat into energy, it enhances memory, it reduces brain fog helping with focus and concentration as part of the production of the neurotransmitter acetylcholine [14].
Itā€™s also great for hair helping with sheen and reducing hair loss.

Vitamin B6 (Pyridoxal 5ā€™-phosphate)
Helps our brain function and the body make theĀ hormonesĀ serotoninĀ (which regulates mood) andĀ norepinephrine (which helps your body cope with stress) [32]. Vitamin B6 also helps our body makeĀ melatonin, which is important in helping regulate your internal clock and your sleep

Vitamin B7 (Biotin)
Depression and fatigue are symptoms of low Biotin levels [2] and it is one of the vitamins that is indispensable for the normal functioning of the brain. The brain needs biotin to make neurotransmitters that keep you feeling mentally alert, happy and attentive. Itā€™s great for hair and nails too.

Vitamin B9 (Folic acid L-5 MTHF)
B9 is essential in the brain for making neurotransmitters and DNA. Supplementation has been shown to reduce depressive symptoms in people with normal and low folate levels [3]Ā 
It also helps with female fertility, reduces inflammation, and helps to balance blood sugar levels.

Vitamin B12 (Methylcobalamin)
Vitamin B12 is crucial for the release of energy, for the production of neurotransmitters and for the normal function of the brain and the nervous system. It is also involved in the formation of red blood cells and helps to create and regulate DNA [15].
The metabolism of every cell in the body depends on vitamin B12. It helps with the release of energy by helping the human body absorb folic acid.
(This is especially important for vegans and vegetarians as the main source of B12 in food is in meat)

Vitamin D3 (Cholecalciferol)
Vitamin D3 is more effective than vitamin D2 at raising blood levels of Vitamin D.
Some types of vitamin D are not vegan-friendly. Vitamin D2 is always suitable for vegans, but vitamin D3 can be derived from an animal source (such as sheepā€™s wool) or lichen (a vegan-friendly source).Ā 

Our vegan friendly D3 activates genes that regulate the immune system and release neurotransmitters (like dopamine and serotonin) that affect brain function and mental health.

Seasonal Affective Disorder (SAD), a mood disorder featuring depressive symptoms, may be due to decreasing levels of vitamin D3, which can be helped by taking supplements.

Vitamin D deficiency impairs and prolongs recovery from depression [6]

Selenium (Methionine)
Studies have shown that selenium improves mood and diminishes anxiety and confusion [4] and lowers the risk of depression [5].
Selenium is also a powerful antioxidant that fights oxidative stress and helps defend your body from chronic conditions.

Microbacteria Blend (Probiotics)
Lactobacillus Acipophilus, Bulgaricus
Bifido Breve, Longum, Infantis
Saccharomyces Boulardii

Psychobiotics are a group of probiotics that improve not only our gut and digestive function but also our brains and moods with antidepressant and anti-stress effects [18]

Did you know that 90% of our serotonin and 50% of our dopamine is made in our gut and not the brain? And that our gut influences our mood, cognition, and mental health.

Stress can lead toĀ changes inĀ both the numbers and types ofĀ bacteria. This can have aĀ knock-on effect for mood via the gut-brain communication system known asĀ the hypothalamic-pituitary-adrenal (HPA) axis.

Probiotics are not just supplements. Probiotic bacteria actually live inĀ the gut microbiome and have science-backed benefits for mental health.

Species ofĀ Bifidobacterium, Lactobacillus are found inĀ the colon where they exert aĀ positive influence onĀ whole body health including alleviating anxiety, memory, and cognitive symptoms and improves our stress resilience.

In this unique blend of probiotics we have included special ones that have an important role in alleviating negative emotions, improving cognitive function, and also relieving psychological stress.

Some Happy Me stories:

Found the me that I knew was in there!
"After suffering from work related stress plus the additional emotional pressure of the pandemic, I realised I had to do something. Also being hypothyroid, I know that my B vit uptake is poor and this affects me with poor energy and foggy brain. After taking these for just a few days, I had better mental clarity, my moods were more balanced as I was not 'jumping' around trying to find normal, my PMS has gone with no more cramps or mood swings. My work anxiety is much more manageable through breathing and taking 'time out'. I now recommend them to my friends and colleagues as they have such a positive impact on me. 10/10"


Yopto verified review

Ā Ā 

Amazing product
"Thank you so much. After one week of using it I'm started to feel again happy! I can't believe how different I am. No mood swings, no madness , no depression I can live Normal life again. Thank you again. Best recommendations."
Yopto verified review

Better than antidepressants
"Iā€™ve been on antidepressants for 3 years and just recently Iā€™ve found they are no longer effective. I have been in quite a bad place until I started taking these. Honestly the difference is wonderful! I am subscribed to monthly orders so hopefully they will continue to work."
Yopto verified review

Full of beans
"As you know I've been taking calm me & energy me for a couple of months now with great results. However I run out of my energy me for a week or so and was unable to put an order in untill payday. In this time I reverted back to how I was feeling before taking your products, and I felt so tired, no motivation and very moody, as I had that heaviness behind my eyes again.Ā 

Although I was still taking calm me and they were helping alot more than if I wasn't taking them, taking both together work so much better for me.
Because of suffering with insomnia and having alot of broken sleep, I was really missing that burst of energy I get from taking energy me. When I received my order a couple of days ago I started to become skeptical, because I was feeling low and tired. I was thinking are they really going to work like last time and get me out of this state that I'm in.
Seriously within an hour of taking 1 energy capsule I was feeling so much better. The heaviness and brain fog had gone and I was back to myself again. I was totally amazed yet again with your products and I can't thank you enough.
I've also started taking happy me and I feel there giving me a extra boost also, I'm up early in the morning and full of beans for the whole day šŸ˜Š.
Once again Evelyn from both myself and my partner, thank you for your products and your support."


Yopto verified review


Itā€™s pretty amazing how nutrients can help isnā€™t it?

We all tend to eat the same sorts of foods each week which means that over time we start to miss some crucial nutrients.

It means that we end up with deficiencies and gaps without even realising it. This has a huge impact on how our bodies and brains work. We adjust and just think that it is our normal. Itā€™s just what we have to put up with.
But this isnā€™t the case.

You can make a change.

Thatā€™s where a high quality supplement can help fix the deficiencies and fill the gaps.

Your health and your life feels transformed.

You have abundant energy and joy comes back into our lives.

Happy Me contains the perfect mix to naturally boost your serotonin levels, to lift your mood, ease your anxiety, to help you relax and sleep better.
Take care,

"I started taking Happy Me to help try and smooth out my mood, linked to my PMT. After 2 cycles I've noticed my mood is more balanced and I'm more positive. I'm sleeping better, too." - Lydia M

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